The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.

Just before the Civil War (but after the South has seceded), Southern saboteurs try to prevent railroad construction from crossing Kansas to the frontier; army captain Nelson is sent out to oppose them. As the tracks push westward, Nelson must contend with increasingly violent sabotage, while trying to romance the foreman's pretty daughter Barbara.

A Mexican bandit is about to be executed in the United States, so his brother takes over a train and holds the passengers as hostages unless his brother is released. Now both the Americans and Mexicans are baffled as to what to do. One of the passengers — who wrote the letter for their captor — has a suggestion: call mercenaries Hank Brackett and Johnny Reech. They do, and as expected they do come up with a plan, but the president of the railroad is not sure if it will work.

U.S. Marshal Johnny Mack Brown once again goes undercover in this Nevada Mckenzie series entry from Great Westerns Prod./Monogram. Masquerading as a parson and a drifter, Sandy Hopkins (Raymond Hatton) and Nevada Jack McKenzie (Mack Brown) come to the aid of the beleaguered residents of Goldville, a small ranching community being terrorized by greedy saloon keeper Ace Benton (Kenneth MacDonald) and his gang of cutthroats. Unbeknownst to the citizenry, the railroad is planning to build tracks through town and Benton is attempting to secure the land by scaring off the settlers.

About to marry Jim Plummer, Kate Foley runs off to Nevada when Ed Bagley convinces her a quick fortune can be made robbing gold shipments that are being transported by the railroad. In Bannock City she meets reformed-bandit Frank Plummer, posing as Frank Norris, brother of Jim Plummer, who has being going straight and working as an express shipment guard. Jim also shows up and plans a robbery by stealing a train and hiding it in an abandoned tunnel. The two brothers are on opposite sides of the law with the now-reformed Kate caught in the middle.

During the Civil War, a Union spy, Andrews, is asked to lead a band of Union soldiers into the South so that they could destroy the railway system. However, things don't go as planned when the conductor of the train that they stole is on to them and is doing everything he can to stop them. Based on a true story.

Not to be confused with the 1929 film The Overland Telegraph, this Western from director Lesley Selander stars Tim Holt as a cowboy appropriately named Tim Holt. In order to hinder the construction of a new telegraph line for his own financial gain, scheming shopkeeper Paul Manning (George Nader) enlists the assistance of a gang of outlaws led by Brad Roberts (Hugh Beaumont in one of his many pre-Leave it to Beaver roles). Unfortunately for the bad guys, Holt and his cohort Chito Rafferty (Richard Martin) sense that there's foul play afoot and embark on an investigation.

It is now an accepted fact that the best of Johnny Mack Brown's Universal westerns were directed by the talented Joseph H. Lewis. Boss of Hangtown Mesa may not be in the same league as the Brown-Lewis classic Arizona Cyclone, but it comes awfully close. This time around, hero Steve Collins (Brown) comes to the aid of Betty Wilkins (Helen Deverell), who has taken over the telegraph-line business established by her uncle John (Henry Hall). The latter was murdered by outlaws who don't cotton to having the territory linked up electronically with the rest of the world.

A town—where everyone seems to be named Johnson—stands in the way of the railroad. In order to grab their land, robber baron Hedley Lamarr sends his henchmen to make life in the town unbearable. After the sheriff is killed, the town demands a new sheriff from the Governor, so Hedley convinces him to send the town the first black sheriff in the west.

An old Chinese man rides into the town of Abalone, Arizona and changes it forever, as the citizens see themselves reflected in the mirror of Lao's mysterious circus of mythical beasts.

After the train station clerk is assaulted and left bound and gagged, then the departing train and its passengers robbed, a posse goes in hot pursuit of the fleeing bandits.

Tom Kenyon and his sidekick Pierre La Farge are hired by rancher Mike O'Day who, with his daughters Toni and Sugar, provides wild horses for the government remount station.