A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.

In order to obtain a stage coach mail contract, a new road must be built. A gang of outlaws try to prevent the building of the road.

A gang of bandits takes control of Tucson in preparation for the arrival of a consignment of gold, with only a band of voluntary soldiers trying to outwit them and save the town.

Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.

A stagecoach is plagued by robberies, but it takes an undercover Wells Fargo agent to discover that a rival company is responsible.

A small-town sheriff in the American West enlists the help of a disabled man, a drunk, and a young gunfighter in his efforts to hold in jail the brother of the local bad guy.

Two investigators for a stagecoach company are assigned to find out why the company's stages keep being ambushed. They discover that the culprits are white men disguised as Indians, and they set out to discover who is behind the plot.

The arrival of the telegraph put Pony Express riders like John Blair and his pal Smoky out of work. A race will decide whether they or stageline owner Drake get the government mail contract.

It's 1876 and all the Indians are at peace except the Comanches lead by Black Cloud. When Black Cloud wipes out a town, only six soldiers are left and they head for the nearest fort. In the desert they are reinforced by members of a stagecoach and find some water at a deserted mission. Pinned down by Black Cloud they send an Indian boy who was Black Cloud's prisoner on to the fort while they try to bargain with Black Cloud whom they learn is without water.

A group of unlikely travelling companions find themselves on the same stagecoach to Cheyenne. They include a drunken doctor, a bar girl who's been thrown out of town, a professional gambler, a travelling liquor salesman, a banker who has decided to embezzle money, a gun-slinger out for revenge and a young woman going to join her army captain husband. All have secrets but when they are set upon by an Indian war party and then a family of outlaws, they find they must all work together if they are to stay alive.

A peace-loving man named Ben Kane takes a job as deputy marshal of Lords, in the old West. Kane is no lawman, but he accepts the badge because he has an old score to settle with the town's chief trouble-maker. Once on the job, Kane must also deal with a young sharpshooter named Billy Young and a sharp and sassy saloon dancer, Lily.

Bounty hunters seek shelter from a raging blizzard and get caught up in a plot of betrayal and deception.