Rufus is a dog but turns into a human with a pendant. He meets a girl named Kat who asks him to go out. Kat is a cat who can also turn into a human as well.

37-year-old Italian-American widow Loretta Castorini believes she is unlucky in love, and so accepts a marriage proposal from her boyfriend Johnny, even though she doesn't love him. When she meets his estranged younger brother Ronny, an emotional and passionate man, she finds herself drawn to him. She tries to resist, but Ronny, who blames his brother for the loss of his hand, has no scruples about aggressively pursuing her while Johnny is out of the country. As Loretta falls for Ronny, she learns that she's not the only one in her family with a secret romance.

Abandoned by his owners, a feisty and playful dog joins a pack of strays and embarks on a journey filled with fun and life lessons in their pursuit to find a new and loving home.

A misanthropic author, a single mother and waitress, and a gay artist form an unlikely friendship after the artist is assaulted in a robbery.

Tabloid reporters are sent by their editor to investigate after the paper recieves a letter from a woman claiming an angel is living with her.

A young couple discovers a secret room filled with cash while house-sitting for rich friends who die while out of the country.

A husband and wife detective team takes on the search for a missing inventor and almost get killed for their efforts.

Baby Dumpling, the six-year-old son of Blondie and Dagwood Bumstead disappears from sight during his first day at school. While Dagwood frantically combs the city in search of the boy, Baby Dumpling spents a nice, safe afternoon with poor little rich girl Melinda Mason, who with her new playmate's help arises from her sickbed to walk across the room for the first time in months.

Blondie and Dagwood are in charge of operations at a mountain motel. The elderly owners of the establishment are in danger of losing their life savings. Among other things, arson threatens.

Dagwood inadvertently gets cornered in to resigning. When his wife Blondie tries to ask Dagwoods boss Mr. Dithers for his job back, he ends up hiring her instead. This doesn't sit too well with Dagwood. Blondie's sister comes to visit, and Dagwood is put in a compromising situation with another woman.

A successful physician and devoted family man, John Dolittle seems to have the world by the tail, until a long suppressed talent he possessed as a child, the ability to communicate with animals is suddenly reawakened with a vengeance! Now every creature within squawking distance wants the good doctor's advice, unleashing an outrageous chain of events that turns his world upside down!

Broadway director Julian Marsh needs just one more hit show so he can retire and recover his health. It looks like he just may pull it off until temperamental star Dorthy Brock breaks her ankle on the eve of the show's premiere and has to be replaced by her understudy Peggy.