New York, I Love You delves into the intimate lives of New Yorkers as they grapple with, delight in and search for love. Journey from the Diamond District in the heart of Manhattan, through Chinatown and the Upper East Side, towards the Village, into Tribeca, and Brooklyn as lovers of all ages try to find romance in the Big Apple.

In late 1960s New York City, fed up with monotonous college life and police repression, free-spirited Fritz, an impenitent seducer and unrestrained party-animal, decides to explore the world. And just like that, as he flees NYC, heading to San Francisco, Fritz embarks on an endless adventure of illumination. Immersed in a world surrounded by drugs and sex, Fritz participates in mad orgies, brings about a revolution, incites mass urban riots, and crosses paths with drug-addled Nazi bikers.

An egotistical saxophone player and a young singer meet on V-J Day and embark upon a strained and rocky romance, even as their careers begin a long uphill climb.

The Duchy of Grand Fenwick decides that the only way to get out of their economic woes is to declare war on the United States, lose and accept foreign aid. They send an invasion force (in chain mail, armed with bows and arrows) to New York and they arrive during a nuclear drill that has cleared the streets.

Sam Clayton's marriage to ex-stripper Freddie comes about when she's strong-armed into the match by Red, a club proprietor who once did her a favor. But Freddie falls in love with Jjaks, Sam's brother, and the pair tries to escape the situation together. It isn't long before both Sam and Red catch up with them, resulting in threats against the two of them -- although tension also starts to build between Sam and Red.

Following a ridiculously awful flight that leads to his pet's death, Nashawn Wade files a lawsuit against the airline, and wins a multimillion-dollar settlement. Determined to create a better flying experience, Nashawn starts his own airline, one that caters to an African-American clientele. Going into business with a tricked-out plane piloted by the smooth Capt. Mack, the airline hits a snag when it has to deal with the family of Elvis Hunkee.

A struggling female soprano finds work playing a male female impersonator, but it complicates her personal life.

Shelley is living a carefree life until a rival gets her tossed out of the Playboy Mansion. With nowhere to go, fate delivers her to the sorority girls from Zeta Alpha Zeta. Unless they can sign a new pledge class, the seven socially clueless women will lose their house to the scheming girls of Phi Iota Mu. In order to accomplish their goal, they need Shelley to teach them the ways of makeup and men; at the same time, Shelley needs some of what the Zetas have - a sense of individuality. The combination leads all the girls to learn how to stop pretending and start being themselves.

Putting its own 'twist' on the story of Oliver Twist, the orange runt of a litter of kittens must fight for survival on the rough streets on New York City, finding unlikely friends in the dogs owned by a down-on-his luck man named Fagin. Soon, Oliver and his new band of comrades must fight for survival when Fagin is unable to pay his debts.

Henry Hackett is the workaholic editor of a New York City tabloid. He loves his job, but the long hours and low pay are leading to discontent. Also, publisher Bernie White faces financial straits, and has hatchet-man Alicia Clark—Henry's nemesis—impose unpopular cutbacks.

Marie-Jo is a middleaged woman living an ordinary life in Marseilles with her husband, Daniel and her daughter, Julie. Daniel runs a small construction business in which Marie-Jo helps. She also works at the local hospital. Outwardly their marriage is loving. But Marie-Jo has been in love with another man for more than twelve months.Marco works as a harbour pilot and is deeply in love with Marie-Jo. Learning that loving two men is impossible, Marie-Jo is forced to make a choice.

On her deathbed, a mother makes her son promise never to get married, which scars him with psychological blocks to a commitment with his girlfriend. They finally decide to tie the knot in Vegas, but a wealthy gambler arranges for the man to lose $65K in a poker game and offers to clear the debt for a weekend with his fiancée.