The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.

A Mexican bandit is about to be executed in the United States, so his brother takes over a train and holds the passengers as hostages unless his brother is released. Now both the Americans and Mexicans are baffled as to what to do. One of the passengers — who wrote the letter for their captor — has a suggestion: call mercenaries Hank Brackett and Johnny Reech. They do, and as expected they do come up with a plan, but the president of the railroad is not sure if it will work.

Hobos encounter a sadistic railway conductor that will not let anyone "ride the rails" for free.

After the train station clerk is assaulted and left bound and gagged, then the departing train and its passengers robbed, a posse goes in hot pursuit of the fleeing bandits.

David Moore is in East Africa to get to his employer's railway construction site. He's accompanied by the owner's son Brian and they've lined up Jack Cuortemayn, reputedly the best guide available, to take them there. Cuortemayn refuses as he doesn't care for the impact the railroad will have on the local inhabitants. While Moore tries to make other arrangements, he meets Ruth Knight who has lived there for many years working with her father in a medical clinic. There will be adventures along the way but when Ruth is captured by slave traders, it's up to the others to rescue her.

During the Civil War, a Union spy, Andrews, is asked to lead a band of Union soldiers into the South so that they could destroy the railway system. However, things don't go as planned when the conductor of the train that they stole is on to them and is doing everything he can to stop them. Based on a true story.

The Wrecker wrecks trains on the L & R Railroad. One of his victims is Larry Baker's father. Baker wants to find the evildoer, among a host of suspects, but it will be difficult since the Wrecker can disguise himself to look like almost anyone

In the rebellious northern frontier province of colonial India, British Army Captain Scott, a young prince and the boy's governess escape by an obsolete train as they are relentlessly pursued by Muslim rebels intent on assassinating the prince.

After avenging the death of his teacher, a Shaolin monk flees China to the American West and helps people while being pursued by bounty hunters.

O'Brien is "Whispering" Smith, so named because he speaks softly but knows how to fend for himself. The son of a railroad president, Smith is determined to learn the business from the ground up, so he gets a job as a track walker for his dad's rail line. While going about his duties, he meets Nan Roberts (Irene Ware), who is about to sell her Colorado ranch. Smith finds out that there are valuable tungsten deposits on her land and makes certain she won't be cheated by the villains

Dan Beattie gives up his lawman job to move further west and rejoin his old war buddy Curt Warren in the town of Sundown. At first mistaken for a railroad agent by Beau Santee, a Sundown businessman who wants to keep the railroad away from his town, Dan is nearly killed by Santee's henchman, Mark Faber. Dan discovers that his old pal Curt works for Santee. Even after learning Dan's true identity, Santee considers him trouble and plots to get rid of him. With the help of Curt's son Stony, Dan tries to get Curt to take a stand on the right side of the law.

A railroad worker in China in 1941 leads a team of freedom fighters against the Japanese in order to get food for the poor.