In California, a group of women struggle with personal problems as their paths intertwine in unexpected ways. Dr. Elaine Keener, the sole caretaker for her aging mother, turns to tarot card reader Christine for spiritual aid. Christine grapples with her own angst due to her lover's debilitating illness. Meanwhile, a bank manager deals with an unwanted pregnancy, two sisters pursue romantic interests and a housewife gets back into the dating game.

In a Paris hotel room, Jack Whitman lies on a bed. His phone rings; it's a woman on her way to see him, a surprise. She arrives and the complications of their relationship emerge in bits and pieces. Will they make love? Is their relationship over? (A prequel to The Darjeeling Limited, 2007.)

A socially awkward and volatile small business owner meets the love of his life after being threatened by a gang of scammers.

Marta (Lucie Patikova) was blinded in an accident brought on by her careless and indulgent younger sister. Now in a school for the blind, Marta keeps up her hope that she will one day see again, mainly because her mother - out of good intentions - has led her to believe that the blindness is only temporary. Before long, Marta comes to realize that her condition will last until she dies, and she begins to despair, hating her mother for giving her false hope. Only a dedicated psychologist, Dr. Mos (Oldrich Navratil) seems to have the means of retrieving Marta from her depression.

A sister and brother face the realities of familial responsibility as they begin to care for their ailing father.

A distraught squatter tries to cope with his werewolf nature through drugs and music.

A grieving man gets a surprise visit from his best friend.

A woman's life is destroyed when she discovers that her husband has another family.

A head chef balances multiple personal and professional crises at a popular restaurant in London.

Five friends in their 20ies try to make it as artists while struggling with psychological disorders and disregulated lives. Abandoned to themselves, they try to escape the pain with drugs and parties, but, soon, that reveals not to be enough. Past violence comes back to the surface, old secrets and addictions get revealed...

When talented young writer Elizabeth Wurtzel earns a scholarship to Harvard, she sees it as her chance to escape the pressures of her working-class background and concentrate on her true talent. But what starts out so promising leads to self-destructive behavior and paralyzing depression that reflects an entire generation's struggle to navigate the effects of divorce, drugs, sex, and high expectations.

Beth, Calvin, and their son Conrad are living in the aftermath of the death of the other son. Conrad is overcome by grief and misplaced guilt to the extent of a suicide attempt. He is in therapy. Beth had always preferred his brother and is having difficulty being supportive to Conrad. Calvin is trapped between the two trying to hold the family together.