Located in Madrid's Plaza del Sol, Km. 0 is the point from which all distances in Spain are measured from the capital. In Km. 0, it is also the meeting point for a gallery of characters. Bored, affluent housewife Marga meets up with gigolo Miguel, who co-habitates with gay Benjamin. Sergio, a soon-to-be-married office clerk who can't wait to lose his virginity, makes the acquaintance of prostitute Tatiana, while gay dancer Bruno meets Maximo. Meanwhile, wannabe director Pedro arranges to meet up with Silvia, an actress who wants to work in musicals directed by Gerardo, and bartender Mario is caught between Amor, who wants to marry him, and her little sister Roma, who is truly in love with him.

A homely but vivacious young woman dodges the amorous attentions of her father's middle-aged employer while attempting to please her glamorously stuck-up roommate Meredith.

The unconventional love story of an aspiring actress, her ambitious driver, and their eccentric boss, the legendary billionaire Howard Hughes.

Vincent and Nefeli just moved in together. They're best friends and swore to never fall in love again. That is until Vincent meets Julie.

Reclusive Rubin Farr teams up with vocal but unsuccessful multi-level salesman Ed Tuttle on a quest to bury Rubin's dead cat in the "perfect spot." Their trip takes them across Utah's desert where they have run-ins with Ed's ex-wife Rula and an elusive Andy Warhol critic.

Gay hair stylist Robin Turner does a lot of work for drag queens, all the while dreaming that he'll someday find the courage to perform in drag himself. When his schizophrenic friend, Liza, turns up looking for a place to stay, the two form an increasingly tight bond, Robin helping Liza through an unplanned pregnancy and Liza pushing Robin to develop a successful nightclub act.

First met when they were duped by an illegal recruiter, Buddy and Sol join forces to solve a mystery that happened inside the house of the former's girlfriend.

Anna, a shy roommate, must deal with the odd demands and behavior of her roommate.

Jean and Bill are a married couple trying to scrape a living. Out of the blue they receive a telegram informing them Bill's long-lost uncle has died and left them his business—a cinema in the town of Sloughborough. Unfortunately they can't sell it for the fortune they hoped as they discover it is falling down and almost worthless.

Two girls with the same name but very different personalities share an apartment in this sequel to Nana. The rising fame of Nana Osaki's band, the Black Stones, is beginning to take a toll on the best friends' relationship. Meanwhile, Nana Komatsu struggles to make sense of her love triangle with Black Stones' guitarist Nobu and rival group Trapnest's bassist Takumi.

Lora Hart manages to land a job in a hospital as a trainee nurse. Upon completion of her training she goes to work as a night nurse for two small children who seem to be very sick, though something much more sinister is going on.

From the affluent sidewalks of Rodeo Drive and the skies high above Beverly Hills. Can she really get her room mates to do what she wants? When they finally give in to temptation, they start to see a side of Cindy they never imagined.