The story centers on the daily life of college dorm roommates Yumi Irisu and Ruka Kujirai. Ruka, the older of the two, is constantly penniless despite her being active in a band. Irisu works part-time at a second-hand bookstore.

Rei Kiriyama is a 17-years-old shogi (Japanese chess) player. He debuted as a professional shogi player when he was in middle school. He lives by himself in Tokyo, because his parents and younger sister died in an traffic accident when he was little. One day, Rei Kiriyama meets three sisters who are his neighbors. The three sisters are Akari Kawamoto, Hinata Kawamoto and Momo Kawamoto. This is his first meeting with someone outside of the shogi world in many years. Having meals with the Kawamoto family brings warm feelings to Rei Kiriyama. As Rei Kiriyama continues his shogi career, his interactions with his neighbors allows him to grow as a shogi player and as a person.

A Tokyo college student is attacked by a ghoul, a super-powered human who feeds on human flesh. He survives, but has become part ghoul and becomes a fugitive on the run.

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Murakami Naoki is the most intelligent student at his high school, but he can't stop obsessing over a girl named Mizuno Haruka. He finally asks her out, and to his surprise, she accepts. After several months of a loving yet obviously doomed romance, it comes time for them to take the entrance exams for Tokyo University. What will happen to their relationship if only one of them is accepted?

The time spent between professional Shogi player Kiriyama and his three stories helps to heal his wounds. As he prepares to secure another win in an upcoming tournament, the father who left the three sisters appears and disturbs the peace.

This 2 night special takes off during their graduation, where Chiaki-senpai & Nodame left for Europe. The first special centered on Chiaki's story, the story tells about Chiaki's dream to be a conductor. Nodame on the other hand attended the conservatory to attain her dream to one-day play the piano for Chiaki. After her hard work, Nodame was given a chance to have a mini recital. During the recital, Chiaki saw her worth and realized that he cannot go on with out her.

As a child, Ono Tsubasa saw a Shirato baseball game on TV and was amazed at the Trumpet player in the band playing. Now, in order to play the Trumpet, she enters Shirato High School. There, she meets Yamada Daisuke, a catcher for the baseball team. With each others support, they go towards their dream of playing at Koushien.

In the dawn of the Meiji period, the Gokumonjou, an inescapable prison, has been established in the middle of an enormous lake to counter the soaring crime rates the new era has brought. Serving as the ferrymen are the famous Kumou brothers: the eccentric family head, Tenka; the reckless but noble second son, Soramaru; and the guileless youngest, Chuutarou. In spite of their grim work, the three lead relatively peaceful lives in the ever-cloudy town of Oumi, together with their housekeeper, Shirasu Kinjou. But buried in the long history of Oumi is the legend of the terrifying "Orochi," a serpentine beast that awakens every three hundred years in a human vessel. Unbeknownst to Soramaru and Chuutarou, the actual job of the Kumou family is to seal the Orochi away before it fully revives—or the world will be plunged into destruction. Amid the monster's next resurrection, the Kumou family must find the resolve to keep laughing under the clouds.

A serial-murderer is on the loose who just so happens to also be removing the hearts of his victims and taking them with him. His victims however, are not merely random humans as thought by the police. They are in fact, the past and present guardians of the gateway of the afterlife.On the day he is to be married, Detective Kanzaki, who happens to be on the case, discovers that his fiancé Mina has been murdered with her heart also missing. He also learns that the killers are Kudo, a geneticist, and his evil secretary Rei. The two are trying to obtain six hearts from the guardians so that they may call forth a horde of demons from the Gate of Rage and have their every desire granted. Only problem is, once they open the gate the entire world will be covered in darkness.

Shiratori Tatsuhiko works as a scout for talent agency Burst in Kabukichō, Shinjuku's red light district, recruiting young girls for the adult entertainment industry. In a business where money means everything, Tatsuhiko finds himself in a constant struggle between rival scouts and the Yakuza.

During spring break, Saki visits her father and has a close encounter with a whale. / Makoto confronts a former classmate. Meanwhile, Saki must make a difficult decision. / Saki is upset after spending the day at her mother's house. Makoto, meanwhile, decides to take a step forward. / After much thought, Saki finally makes a decision.