Focuses on three very different siblings, all searching for happiness. Hans-Jörg is a sex addicted librarian, who is interested in young students. Werner is a successful politician with a dysfunctional family. Agnes, a trans woman, works as a table dancer in a night club. The three brothers just have one thing in common: their longing for a happy life.

Louise, who has just written a novel, comes to Paris to meet with a potential publisher. While in the city, she stays with her older sister, Martine, who in many ways is the exact opposite of Louise: she lives in a fashionable neighborhood, is cold to others, and has snobby friends, while Louise lives in a small town and is thoroughly unpretentious. Louise's apparent happiness -- and similarities to their mother -- gradually gets on Martine's nerves.

Aspiring Florida defense lawyer Kevin Lomax accepts a job at a New York law firm. With the stakes getting higher every case, Kevin quickly learns that his boss has something far more evil planned.

Marie, who works as a successful door-to-door encyclopedia salesperson, has been married to her husband Francois for 12 years and has a two-year-old son. Though she is relatively content with her life, she feels something is wanting. Enter 50-year old African-American Bill. Initially she is annoyed by his insouciance, but she finds that she is irresistibly attracted to him. Soon the two are in the midst of sordid illicit affair. She knows little about her new lover, and he seems uninterested in learning about her, but the long sessions of lovemaking are something else entirely. Feeling out of control, Marie is increasingly repelled by her own actions. Psychologically, she struggles to reconcile her torrid encounters with Bill and mundane domestic chores such as bathing her son. Moreover, she finds herself incapable of hiding her adulterous behavior, rather she comes home with scratches and hickeys all over her body, to the devastation Francois.

A Jewish woman named Jettel Redlich flees Nazi Germany with her daughter Regina, to join her husband, Walter, on a farm in Kenya. At first, Jettel refuses to adjust to her new circumstances, bringing with her a set of china dishes and an evening gown. While Regina adapts readily to this new world, forming a strong bond with her father's cook, an African named Owuor.

Charlie Kaufman is a confused L.A. screenwriter overwhelmed by feelings of inadequacy, sexual frustration, self-loathing, and by the screenwriting ambitions of his freeloading twin brother Donald. While struggling to adapt "The Orchid Thief," by Susan Orlean, Kaufman's life spins from pathetic to bizarre. The lives of Kaufman and Orlean's book become strangely intertwined as each one's search for passion collides with the other's.

A manager of an orphanage in India is sent to Copenhagen, Denmark, where he discovers a life-altering family secret.

A female traveling companion seduces a married man and his alcoholic wife.

Karel and Saša's marriage has reached a dead end, so Saša moves out of the house for a while. She finds temporary refuge with Dušan, an old acquaintance who once played at their wedding. Both of them, sometimes together, sometimes separately, explore the elusive topic of relationships and shed light on it from their opposite perspectives.

Fabio and Leticia live a marriage crisis. He suspects that she cheats on him, and starts to chase her into a journey through the city night.

A doctor's marriage to a single mother comes unravelled.

When a new neighbour arrives at Rannveig´s doorstep, her frustrated everyday life suddenly changes. The cloud of hopelessness that surrounds her marriage and her relationship with her almost adult daughter lifts temporarily but soon the family is forced to confront new and unknown challenges in their relationship.