Myron Breckinridge flies to Europe to get a sex-change operation and is transformed into the beautiful Myra. She travels to Hollywood, meets up with her rich Uncle Buck and, claiming to be Myron's widow, demands money. Instead, Buck gives Myra a job in his acting school. There, Myra meets aspiring actor Rusty and his girlfriend, Mary Ann. With Myra as catalyst, the trio begin to outrageously expand their sexual horizons.

Marco, a teacher from Milan, relocates to Palermo and takes a temporary job teaching in a juvenile detention centre while he waits for a high school teaching position. He tries to understand and motivate his handful of students, encouraging them to stand up for their rights, finding out about their histories: Natale, in for murder and enamored with the Mafia; Pietro, who can't seem to stay out of jail; Claudio, barely 14 and learning to stand up for himself; and Mery, a trans sex worker, who was arrested after a fight with a trick who didn't want to pay her, and is now stuck in a male prison.

Tom of Finland is one of the gay world's few authentic icons. His drawings have had an enormous influence on gay identity. Tom's ultimate leather men are known and seen everywhere. They are symbols of gay pride and friendship. The documentary includes some titillating 'enactments' inspired by Tom's art work.

Xiao Bo lives in a world where the lines defining men from women are constantly dissolving. He kneels at the deathbed of his father who has become a woman, and whose dying wish is to have oral sex with his/her son. His boyfriend Nana has also undergone a sex change, but Xiao Bo no longer finds her attractive as a woman. A sexual chain reaction ensues that wreaks havoc on traditional Chinese roles that govern male and female, parent and child.

A love story, a love triangle that gets soiled with blood with the arrival of a fourth character: a serial killer who collects vaginas. Lesbian couple is chased by lover betrayed in the areas of Weird. Blood and sex in the tradition of the 80's Boca do Lixo films with eschatological scenes and total cinematographic metalanguage.

Serap, who has been living in the darkest streets of Beyoglu, is a charming woman in her 20s. A beautiful woman's way of prostitution and prostitution living in the back streets of Beyoglu as a person intersects with him when a magical love begins. Hakan tries to take the pimp of Serap as a madman. The man who doesn't have the job can't do it. One day when Serap finds his lover Hakan in a scene he never thought possible, his whole life is deeply shaken. Serap will now be in a different life, running for different purposes.

When Gerda Wegener asks her husband Einar to fill in as a portrait model, Einar discovers the person she's meant to be and begins living her life as Lili Elbe. Having realized her true self and with Gerda's love and support, Lili embarks on a groundbreaking journey as a transgender pioneer.

When Sid comes out as a woman, a 14-year-old boy named Ralph literally shows up at her door announcing that Sid is his dad. Ralph is surprised to discover that his father is now a woman, but thinks having a transgender dad is pretty cool. But Ralph hasn't told his mother and stepdad that he’s tracked down his biological father. And then there is Sid’s boyfriend Daniel, who has yet to tell his family of his relationship with Sid. Daniel is nowhere near ready to accept Ralph as a stepson and complicate his life further. Sid’s coming out has a snowball effect that forces everyone out of the closet. What happens when gender, generations and cultures collide to create a truly modern family?

A trans-sexual man return to his hometown to finish the bureaucratic process to become officially a male. But the public servant who should implement this simple bureaucratic operation is Giorgio, his first and only boyfriend.

Guerrino, a prematurely widowed businessman, falls in love with Chantal, a former paratrooper in the German army who changed sex a few years earlier.

A diverse group of artists and bohemians gathers at a party to celebrate and wait for a guest of honor named Pedro. As they drink, talk, and wander through the rooms, the much-anticipated Pedro never arrives, turning the event into a surreal, endless vigil. The guests are left to navigate their own desires and existential boredom while hearing the rhythmic "tam-tam" of drums that suggests a coming catastrophe.

In Kentucky, a transgender woman and her best male friend lament the lack of eligible partners and step across old boundaries of love and romance.