When a bored Sherlock eagerly takes the case of Gabrielle Valladon following an attempt on her life, the search for her missing husband leads to Loch Ness and the legendary monster.

Tom and Jerry need to learn to work together in order to help Sherlock Holmes with an investigation of a jewel theft. But still, they are cat and mouse!

Holmes takes a vacation and visits his old friend Sir Henry Baskerville. His vacation ends when he suddenly finds himself in the middle of a double-murder mystery. Now he's got to find Professor Moriarty and the horse Silver Blaze before the great cup final horse race.

In a mansion full of secret rooms and passageways, people are dying shortly after seeing the ghost of a woman in gray, as an old legend dictates. Called in to solve the mystery, Sherlock Holmes has doubts about the supernatural aspect of the crimes and focuses on a more earthly culprit.

In World War II, a British secret agent carrying a vitally important document is kidnapped en route to Washington. The British government calls on Sherlock Holmes to recover it.

During WWII several murders occur at a convalescent home where Dr. Watson has volunteered his services. He summons Holmes for help and the master detective proceeds to solve the crime from a long list of suspects including the owners of the home, the staff and the patients recovering there.

After the King of Rovenia has been assassinated, Holmes and Watson are engaged to escort his son to Europe via Algiers, aboard a transatlantic ocean liner which also carries a number of suspicious persons, any of whom may be involved in a plot to also assassinate him.

Sherlock Holmes and Watson are on the trail of a criminal and scientific mastermind who seems to control monsters and creations which defy belief.

Sherlock Holmes is drawn into the case of Jack the Ripper, who is killing prostitutes in London's East End. Assisted by Dr. Watson, and using information provided by a renowned psychic, Robert Lees, Holmes finds that the murders may have their roots in a Royal indiscretion and that a cover-up is being managed by politicians at the highest level, all of whom happen to be Masons.

Sherlock Holmes investigates when young women around London turn up murdered, each with a finger severed. Scotland Yard suspects a madman, but Holmes believes the killings to be part of a diabolical plot.

A gang of sharp witted street kids save Sherlock Holmes from an accusation of murder and to help foil an audacious robbery.

Holmes and Watson board a passenger train bound from London to Edinburgh, to guard the Star of Rhodesia, an enormous diamond worth a fortune belonging to an elderly woman of wealth; but within the first hour of the trip, the woman's son is murdered and the diamond stolen and any of the passengers in their car could be the killer thief.