What happens when a glamorous express, with high government officials, wealthy merchants, concubines and a gang of brigands on board, speeds towards the small town of Hanshui, where escaping bank robbers, corrupt officials, and gamblers await? Well, let's just say the Titanic had a smoother maiden voyage.

When the local sheriff is killed after a bank robbery, ex-lawman Ben Cutler collars the apparent killer, Eddie Campbell. Because of his background as a local youth who spent time living with the Cutlers, Eddie gets the benefit of the doubt from Ben's daughter and his wife-to-be. Ben is firm in his belief that Eddie is guilty, and as the matter is debated in a divisive court battle, it will soon become clear whether he's right.

When three Texas Rangers try to investigate kidnapped Mexicans being used as forced labor in the mines of Silver Bullet, they are framed for murder by the town's corrupt sheriff.

Stephen Westcott and Ed Martin scheme to put Jane Travers' wagon line out of business. They want to use it take over all the wagon- train traffic going west. Hoppy, California and Lucky must make sure that doesn't happen.

When he runs for sheriff, Hoppy is beaten by Jerry Doyle, the gutless wonder voted for by every crook in town. When Hoppy moves to have the new sheriff impeached, outlaw leader Tad Hammond hires forty gunslingers to stop him. Stop Hoppy? Hah!

Hoppy and Lucky have been called in to investigate a series of stage holdups. The robbers are taking gold from Colby's mine and Hoppy suspects it may be ex-outlaw Colby himself. When Speedy strikes gold, Hoppy borrows it and announces a gold shipment hoping to catch the gang and their leader.

Hoppy, Lucky and California search for a mine owned by Trudy Pendleton after it was taken from her by thw swindling gambler Ace Gibson. They find the mine and Hoppy fights Gibson over it.

Finishing a trail drive, Hoppy and the boys head to town and immediately get caught up in the conflict between school teacher Miss Abott and next door saloon owner Mawson. When Miss Abott disappears, Hoppy gets a clue to her location and rescues her from Mawson's cabin. It looks like Mawson is the man he wants, but Hoppy finds an item that indicates otherwise.

Sue Morgan gets Hoppy and his friends to join their expedition looking for Indian artifacts. Expedition leader Atwood makes a deal with nearby cattle rustler Morgan to loot the Indian treasures instead and sell them. Hoppy is on to their plan and pretending to leave follows them. Not only is he outnumbered by Morgan's men, but California has himself about to be sacrificed in an Indian ritual.

Hoppy is busy chasing stagecoach bandits who sing as they rob.

Lee Garvin has eloped with the daughter of a railroad man who didn't approve of the marriage. Hoppy steps in when the young man is framed for murder.

European bad guy Baron Bendor leads some local townsmen in a plot to obtain horses through theft. Hoppy and his sidekicks Lucky and Speedy must find and expose the horse thieves.