Elizabeth has just been through a particularly nasty breakup, and now she's ready to leave her friends and memories behind as she chases her dreams across the country. In order to support herself on her journey, Elizabeth picks up a series of waitress jobs along the way. As Elizabeth crosses paths with a series of lost souls whose yearnings are even greater than her own, their emotional turmoil ultimately helps her gain a greater understanding of her own problems...

Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.

In the years before World War II, a penniless Japanese child is torn from her family to work as a maid in a geisha house.

Ramón Sampedro is a ship mechanic and part-time poet left a quadriplegic following a diving accident. Ramón fought for 30 years for the legal right to end his own life. He develops close relationships with his long-term lawyer Julia and his friend Rosa, who tries to convince him that his life is worth living. Despite his situation, Ramón manages to inspire those around him to live life to the fullest.

Focuses on three very different siblings, all searching for happiness. Hans-Jörg is a sex addicted librarian, who is interested in young students. Werner is a successful politician with a dysfunctional family. Agnes, a trans woman, works as a table dancer in a night club. The three brothers just have one thing in common: their longing for a happy life.

Louise, who has just written a novel, comes to Paris to meet with a potential publisher. While in the city, she stays with her older sister, Martine, who in many ways is the exact opposite of Louise: she lives in a fashionable neighborhood, is cold to others, and has snobby friends, while Louise lives in a small town and is thoroughly unpretentious. Louise's apparent happiness -- and similarities to their mother -- gradually gets on Martine's nerves.

Lincoln Hawk a hard-luck big-rig trucker takes us under the glaring Las Vegas lights for all the boisterous action of the World Armwrestling Championship. Relying on wits and willpower, Hawk tries to rebuild his life by capturing the first-place prize money, and the love of the son he abandoned years earlier into the keeping of his rich, ruthless father-in-law.

Hell's Kitchen, New York. Terry Noonan returns home after a ten-year absence. He soon reconnects with Jackie, a childhood friend and member of the Irish mob, and rekindles his love affair with Jackie's sister Kathleen.

A posthumous look at the last days of Guenther's life as he, his best friend, and his sister let loose on a four-day binge of alcohol, drugs, and sex.

The murderous, backwoods Firefly family take to the road to escape the vengeful Sheriff Wydell, who is not afraid of being as ruthless as his target.

Two young Nicaraguan children, Saslaya and her mute brother Dario, must travel to Costa Rica to find their long-lost mother.

In 1950s New York, a department-store clerk who dreams of a better life falls for an older, married woman.