Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.

Two criminal drifters without sympathy get more than they bargained for after kidnapping and holding for ransom the surrogate mother of a powerful and shady man.

Two friends named Gerry become lost in the desert after taking a wrong turn. Their attempts to find their way home only lead them into further trouble.

A group of Mexican emigrants attempts to cross the Mexican-US border. What begins as a hopeful journey becomes a harrowing, bloody and primal fight for survival when a deranged, rifle-toting vigilante and his loyal Belgian Malinois dog chase the group of unarmed men and women through the treacherous borderland. In the harsh, unforgiving desert terrain, the odds are stacked firmly against them as they discover there’s nowhere to hide from the unrelenting, merciless killer.

When Camille falls ill, she is forced to live with Philibert and Franck.

A recent widow invites her husband's troubled best friend to live with her and her two children. As he gradually turns his life around, he helps the family cope and confront their loss.

Anthropology student Daria, who's helping a property developer build a village in the Los Angeles desert, and dropout Mark, who's wanted by the authorities for allegedly killing a policeman during a student riot, accidentally encounter each other in Death Valley and soon begin an unrestrained romance.

When an abused wife grows to giant size because of an alien encounter and an aborted murder attempt, she goes after her cheating husband with revenge on her mind.

A tribe survives in the middle of the desert on the meager pickings of a barren landscape. Soo'goh, the weakest member of the clan, seeks to overcome all obstacles and to reach the green pastures of the paradise that they all yearn for.

At the beginning of the 20th century an American woman is abducted in Morocco by Berbers, and the attempts to free her range from diplomatic pressure to military intervention.

Struggling actor John Person agrees to drive a blue suitcase from Los Angeles to the small town of Baker, Calif., and hand it over to a mysterious cowboy in return for having his credit card debt of $27,000 paid off. Upon his arrival, John can't find the cowboy but receives an ominously head-shaped package he's supposed to hang onto. While waiting, John gets close to Ruthie, whose psychotic boyfriend, Randy, keeps threatening to kill him.

One-armed war veteran John J. Macreedy steps off a train at the sleepy little town of Black Rock. Once there, he begins to unravel a web of lies, secrecy, and murder.