Hard times come for the Carraclough family and they are forced to sell their dog, Lassie, to the rich Duke of Rudling. Lassie, however, is unwilling to remain apart from young Carraclough son Joe and sets out on a long and dangerous journey to rejoin him.

On their way to start a new life at a sheep farm in rural Virginia, the Turner family are halted by a wreck on the highway that has claimed the life of a truck driver. Spotting the trucker's now-abandoned collie on the side of the road, they take pity on the dog and adopt her. As the city family copes with the change to rural life, including a feud with a neighboring farm family who resent the city interlopers, the ever-loyal Lassie helps them adjust to their new surroundings.

A family in financial crisis is forced to sell Lassie, their beloved dog. Hundreds of miles away from her true family, Lassie escapes and sets out on a journey home.

John is a cheerful and energetic young boy, who lives in a small coal-mining town in England. One day he finds a small dog lost in a flock of sheep. John takes him back home and names the puppy Lassie. Soon they become good friends, just like real siblings. Lassie is a very lovely and smart dog, so everyone in the town loves her very much. But their happy life doesn't last long. Suddenly a coal-mine owner closes his company because there is no more coal left in the coal mine. John goes to meet the coal-mine owner to request a further investigation. The owner accepts John's request, but in exchange for that, he takes Lassie to Scotland. Priscilla, the owner's granddaughter and also John's friend, cannot just stand by and let Lassie suffer in a cage. She opens the cage and sets Lassie free. Lassie sets out on a very long and hard journey from Scotland to her hometown.

In this touching drama a disparate group of people rally together to save a dog that has fallen into a deep well.

When Lassie's master dies, an old friend tries to convince a judge that the dog's life should be spared.

Lassie is claimed from his family by a "former owner" and then braves a cross country trip to rejoin the ones that love her.

During a hurricane in Florida, Lassie becomes trapped on a ship bound for Hawaii and ends up overboard. After being rescued by a dolphin and reaching Virginia, she is mistaken for a dangerous stray in Williamsburg, where an elderly lawyer and his assistant come to her defense.

After years of prospecting, Jonathan finally strikes gold. He returns to town only to discover that his partner has since died and left Tommy fatherless. He decides to leave Shep with Tommy to cheer him up. Meanwhile, Jonathan's new partner isn't interested in sharing the gold, and lures Jonathan to his death.

Bill's separated from his litter, making friends with the wild creatures until he's found and adopted by young Kathie. An accident separates him from her, and he's drafted into K-9 duty in the trenches until battle fatigue takes its toll and he turns vicious. And even though he finds his way back home, he may be condemned as a killer.

The Stratton kids, Samantha and Chip, and their grandmother, Ada, drive to visit their Uncle Stuart. Grandma collapses and dies in a strange town, leaving the kids and Lassie on their own.

Flo and his trusted Collie pal Lassie spend the summer at Aunt Cosma's, alongside her foster children Kleo and Henry, and her dog Pippa. When local canines start disappearing, including Pippa, Lassie rallies the kids to solve the mystery.