Guerrino, a prematurely widowed businessman, falls in love with Chantal, a former paratrooper in the German army who changed sex a few years earlier.

In Kentucky, a transgender woman and her best male friend lament the lack of eligible partners and step across old boundaries of love and romance.

Paul and Kim meet when their vehicles collide. Paul is fascinated with the attractive Kim. It turns out that the two were childhood friends in Catholic boys' school, but back then, before the operation, Kim was named Karl.

This sensitive and sensual film draws together several narratives spanning several decades, all of them transpiring in the same room of the same Singaporean hotel — and all of them involving sex.

Three intersecting stories of transgender romance explore the boundaries of love, culture and identity across three generations.

A grieving husband struggles to come to terms with his wife's passing. Following a night-time visit to her grave, he picks up a transgender sex worker.

Ari can’t satisfy his wife Sara. He crashes his speedboat into a cliff and winds up in Switzerland for rehabilitation in what may or may not have been a suicide attempt. Alex, commissioned to paint Sara’s portrait by Ari, becomes Sara’s house guest and sex partner in Ari’s absence. Teresa, Ari’s secretary and ex-lover, is jealous of Sara’s relationship with Alex and schemes to break them up.

Myron Breckinridge flies to Europe to get a sex-change operation and is transformed into the beautiful Myra. She travels to Hollywood, meets up with her rich Uncle Buck and, claiming to be Myron's widow, demands money. Instead, Buck gives Myra a job in his acting school. There, Myra meets aspiring actor Rusty and his girlfriend, Mary Ann. With Myra as catalyst, the trio begin to outrageously expand their sexual horizons.

Marco, a teacher from Milan, relocates to Palermo and takes a temporary job teaching in a juvenile detention centre while he waits for a high school teaching position. He tries to understand and motivate his handful of students, encouraging them to stand up for their rights, finding out about their histories: Natale, in for murder and enamored with the Mafia; Pietro, who can't seem to stay out of jail; Claudio, barely 14 and learning to stand up for himself; and Mery, a trans sex worker, who was arrested after a fight with a trick who didn't want to pay her, and is now stuck in a male prison.

Xiao Bo lives in a world where the lines defining men from women are constantly dissolving. He kneels at the deathbed of his father who has become a woman, and whose dying wish is to have oral sex with his/her son. His boyfriend Nana has also undergone a sex change, but Xiao Bo no longer finds her attractive as a woman. A sexual chain reaction ensues that wreaks havoc on traditional Chinese roles that govern male and female, parent and child.

Serap, who has been living in the darkest streets of Beyoglu, is a charming woman in her 20s. A beautiful woman's way of prostitution and prostitution living in the back streets of Beyoglu as a person intersects with him when a magical love begins. Hakan tries to take the pimp of Serap as a madman. The man who doesn't have the job can't do it. One day when Serap finds his lover Hakan in a scene he never thought possible, his whole life is deeply shaken. Serap will now be in a different life, running for different purposes.

When Gerda Wegener asks her husband Einar to fill in as a portrait model, Einar discovers the person she's meant to be and begins living her life as Lili Elbe. Having realized her true self and with Gerda's love and support, Lili embarks on a groundbreaking journey as a transgender pioneer.