Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.

Sayaka, a high school student, kills herself but the reason behind her suicide is unknown. She appeared to have led a normal life with her family. Her mother Rumiko seemed to have raised Sayaka with love and care. In reality, that does not seem to be the case. When the mother and daughter recall the same incidents that took place in the past, they tell very different stories.

Brad and Kate have made something of an art form out of avoiding their families during the holidays, but this year their foolproof plan is about go bust -- big time. Stuck at the city airport after all departing flights are canceled, the couple is embarrassed to see their ruse exposed to the world by an overzealous television reporter. Now, Brad and Kate are left with precious little choice other than to swallow their pride and suffer the rounds.

Max is a former playboy who has decided to settle down by marrying his current love, Muriel. However, when Max catches a glimpse of the great lost love of his life, he becomes obsessed with rekindling their relationship.

Fahri attracted many women, including Maria, Nurul, and Naora. They hide their feelings until Fahri's marriage with Aisha which broke their hearts.

Hard-drinking novelist Zach Hutton spirals out of control after his wife and mistress both leave him. Alone and crippled by a bad case of writer's block, Zach slips in and out of casual relationships and one-night stands, while his drinking becomes more and more severe. With the help of a bartender and his therapist, Zach confronts his demons — women and alcohol.

After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.

While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.

A socialite couple thinks only of themselves. When they become bored with one another, they divorce and marry others (several times). The person who suffers most from their cavalier outlook on life is their cute little daughter Mary Jane Irving.

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Wealthy socialite Charlotte Cartwright and her dear friend Alice Pratt, a working class woman of high ideals, have enjoyed a lasting friendship throughout several decades. Recently, their lives have become mired in turmoil as their adult children’s extramarital affairs, unethical business practices, and a dark secret threaten to derail family fortunes and unravel the lives of all involved. Charlotte and Alice decide to take a breather from it all by making a cross-country road trip in which they rediscover themselves and possibly find a way to save their families from ruin.

Karin and Peter have been married for almost 15 years. From the outside, they seem happy, but behind the closed doors of the house there is a repression. Then the dog Orion steps into their lives ...