Jim Varney's recurring dim-bulb character Ernest P. Worrell returns in this film as a school janitor seeking to obtain a high school diploma.

In a bid to save her son's end-of-school camping trip, a single mom steps in as the bus driver while trying to show him she really can be a cool mom.

In a time and place where abortion is illegal, a husband rejoices at the news of pregnancy while his wife secretly attempts to terminate it. After failed attempts through jumping, running, and medication, she encounters a strange bus and its peculiar driver.

In August 1996, bus drivers Marcel Van Loock and Wim Moreels are apprehended by the Moroccan Customs for drug trafficking. Inside their bus, hidden behind a false compartment, they have discovered 700 pounds of hashish. Although the owner of the bus company is arrested as well and makes a full confession clearly indicating that both drivers were unaware of the hidden drugs, the Moroccan judge sentences both men to 5 years in the Moroccan prison of Tangiers. Nothing could have prepared the two men for life inside a Moroccan prison. Without food, clothes or medical care, they must learn how to take care of themselves to survive their stay in prison. Corrupt guards, corrupt lawyers and judges, a consul who doesn't care and frequent beatings are only part of the terrible prison. Meanwhile their families at home are left without any information, any help or any hope - finding out that their own government doesn't care for Belgian people in prisons abroad.

Set in the Bronx during the tumultuous 1960s, an adolescent boy is torn between his honest, working-class father and a violent yet charismatic crime boss. Complicating matters is the youngster's growing attraction - forbidden in his neighborhood - for a beautiful black girl.

Cristina is a rich, spoiled princess visiting Rome with her royal parents. The mission of their visit is to marry her off to a super-wealthy corporate type and thereby start to turn around the losses their small kingdom is experiencing in its casino business. These less-than-noble intentions get derailed when Barnaba, a zany bus driver enters their lives and falls madly in love with the gorgeous Cristina. He is nuts enough to succeed in this romantic chase after royalty, as love seems to fuel his determination to rid Cristina of her elitism and to make her see his own irrepressible attractions.

In several unrelated stories, the consequences of putting one's foot down – or failing to do so – are explored.

Southern matriarch Madea has a lot on her plate. Her nieces, Vanessa and Lisa, have relationship troubles - Vanessa moves into Madea's house with her 2 young children and Lisa is engaged to a controlling man that her mother set her up with. In addition, Madea has just been court-ordered to become the guardian of Nikki, a rebellious runaway teenager. Madea must keep the peace and her family together while simultaneously planning her clan's reunion.

A Glasgow man visits war-torn Nicaragua with a refugee tormented by her memories.

Good hearted but not very wordly-wise, Dante is happy driving the school bus for a group of mentally handicapped children, while feeling he is somehow missing out on life and love. So he is very excited when after nearly being knocked down by her car he meets Maria, who seems immediately enamoured of him. He is soon invited to her sumptuous Palermo villa, little suspecting that this is part of a plot. He bears an amazing likeness to Maria's stool-pigeon gangster husband and it would be convenient for them if the mobster, in the shape of Dante, was seen to be dead and buried.

Two bumbling service station attendants are left as the sole beneficiaries in a gangster's will. Their trip to claim their fortune is sidetracked when they are stranded in a haunted house along with several other strangers.

A defrocked Episcopal clergyman leads a bus-load of middle-aged Baptist women on a tour of the Mexican coast and comes to terms with the failure haunting his life.