A rich but unscrupulous old woman plots with a scientist to have her brain implanted in the skull of a sexy young woman.

Dr Simon Helder, sentenced to an insane asylum for crimes against humanity, recognises its director as the brilliant Baron Frankenstein, the man whose work he had been trying to emulate before his imprisonment. Frankenstein utilises Helder's medical knowledge for a project he has been working on for some time. He is assembling a man from vital organs extracted from various inmates in the asylum. And the Baron will resort to murder to acquire the perfect specimens for his most ambitious project ever.

The Wolf Man tries to warn a dimwitted porter that Dracula wants his brain for Frankenstein monster's body.

Frankenstein's unscrupulous colleague, Dr. Bohmer, plans to transplant Ygor's brain so he can rule the world using the monster's body, but the plan goes sour when he turns malevolent and goes on a rampage.

Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.

Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.

A student receives a serial killer's brain in a transplant after being thrown into a pool with no water in it.

Rescued from the guillotine by his devoted dwarf Fritz, the Baron relocates to Carlsbruck, where he continues his gruesome experiments.

An evil scientist implants the brain of a murdered high school student into an animatronic Tyrannosaurus, who later wreaks vengeance on the bullies who killed him, and is reunited with his sweetheart.

University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.

A strikingly beautiful and wealthy woman is hit by a truck and is all smashed up and nearly killed. At nearly the same time, a very plain looking lower middle class woman simply faints and suffers brain death. The beautiful womans brain is fine, so, doctors merely transplant her brain into plain Jane. Problems ensue when plain Janes husband continues to believe she is still his wife. She has no memory of him, and goes to live with the beautiful womans husband. She doesn't mix well with her new socialite friends and family. Mirrors are emotional battlefields as well.

The discovery of a perfectly preserved caveman prompts a mad scientist to attempt a daring brain transplant.