Buck Roberts is leading a wagon train of railroad supplies and Jim Corkle and his henchman Loder are out to stop them by using white men dressed as Indians for the attacks.

Fuzzy purchases a saloon with a large sack of gold from the mine he owns with his partner Billy. When a crooked lawyer uses underhanded methods to try taking over the saloon, Billy works to bring the lawyer and his no-good gang to justice.

The fastest gun in the West tries to escape his reputation.

Bob Ford murders his best friend Jesse James in order to obtain a pardon that will free him to marry his girlfriend Cynthy. The guilt-stricken Ford soon finds himself greeted with derision and open mockery throughout town. He travels to Colorado to try his hand at prospecting in hopes that marriage with Cynthy is still in the cards.

A former outlaw becomes a Wells Fargo guard, but when the stagecoach is robbed, he becomes a wanted man once again.

Just as Nevada wins $7000 in yellowback bills, Ben Ide takes his $7000 and heads out to buy mining equipment. Burridge has his man Powell kill Ide and retrieve the money and Nevada finds Ide just as the posse arrives. Found with the money Nevada is arrested and Burridge now gets Powell to incite the local citizens to lynch Nevada.

With the California Gold Rush beginning, Senator Frost's singing daughter Caroline loves a young army officer; the Senator can't stand him, and has him sent to California. Headstrong Caroline follows him by train, riverboat, and covered wagon, gaining companions en route: a vagrant Russian prince and gambler Johnny Lawlor, who just might take her mind off the army.

On the outskirts of town, the hard-nosed Vienna owns a saloon frequented by the undesirables of the region, including Dancin' Kid and his gang. Another patron of Vienna's establishment is Johnny Guitar, a former gunslinger and her lover. When a heist is pulled in town that results in a man's death, Emma Small, Vienna's rival, rallies the townsfolk to take revenge on Vienna's saloon – even without proof of her wrongdoing.

A former sheriff relentlessly pursuing the 7 men who murdered his wife in Arizona crosses paths with a couple heading to California.

Monte Walsh and Chet Rollins are long-time cowhands, working whatever ranch work comes their way, but "nothing they can't do from a horse." Their lives are divided between months on the range and the occasional trip into town. Monte has a long-term relationship with prostitute Martine Bernard, while Chet has fallen under the spell of the widow who owns the hardware store. Camaraderie and competition with the other cowboys fill their days, until one of the hands, Shorty Austin, loses his job and gets involved in rustling and killing. Then Monte and Chet find that their lives on the range are inexorably redirected.

When two US cavalrymen transporting a gold shipment get killed, US Army Intelligence investigator John Haven goes undercover to a mining and logging town to find the killers.

Saloon-bar singer Freddie gets very angry whenever boyfriend Blackie seems to be playing around. She always packs a six-shooter, so this is bad news for anything that happens to be in the way. As this is usually the local judge's rear-end, Freddie and friend Conchita are soon hiding out teaching school in the middle of nowhere.