Five friends set out for a weekend at a remote cabin in the woods, expecting nothing more than fun and relaxation. As night falls, they discover that something far more unsettling is at work and that nothing about their getaway is what it seems.

Under a powerful Mayan curse, snakes are hatched inside a young woman, slowly devouring her from within. Her only chance for survival is a powerful shaman who lives across the border. With only hours to live, she jumps on a train headed for Los Angeles. Unfortunately for the passengers aboard, they are now trapped, soon to be victims of these flesh-eating vipers.

While stationed in Asia, six American G.I.'s witness the secret ritual of Lamians (worshipers of women who can change into serpents). When discovered by the cult, the High Lamian Priest vows that "the Cobra Goddess will avenge herself". Once back in the United States, a mysterious woman enters into their lives and accidents begin to happen. The shadow of a cobra is seen just before each death.

Secluded mountain village in northern Fujian is in a state of panic. On the wedding day of Dong Wenhui and Qian Xiuchen father of the groom was tragically swallowed by a python. When Dong Wenlin threw the snake corpse on the altar, the python king swore to revenge. The story of the movie originated from the primitive snake culture in northern Fujian. According to legend, since the Qin and Han dynasties, the ancestors believed in snakes as the god of ancestors and worshiped them as totems. They do not fight snakes or eat snake meat. . This custom has been preserved to this day, and many ancient myths have also been derived. Among them, the legend of "The Long Snake Immortal Marries His Wife" is the most popular, and "Mutated Python" is based on this adaptation.

After an overly ambitious businessman transports an 80-foot python to the United States, the beast escapes and starts to leave behind a trail of human victims. An FBI agent and a snake specialist come up with a plot to combat the creature by pitting it against a bioengineered, 70-foot boa constrictor. It's two great snakes that snake great together!

After his fiancé sudden death, Qin Yu is convinced Cass Corporation is somehow involved and is determined to find the truth. Booking passage on the same cruise ship as former Cass employee, Jason, Qin Yu follows him. Qin Yu hopes to secure the information he needs on Cass to be able to testify against them in court. But Qin Yu isn’t the only person on board hoping to gain intel on Cass. Desperate for a story, reporter Feng Li tails both Qin Yu and Jason, booking passage on the same cruise. Unfortunately, no one has much of a chance to gain information as the ship is suddenly attacked by giant mutant snakes. Escaping the attack, the survivors find themselves on the very island Cass Corporation has been conducting their illegal experiments. Hunted by monsters of all sorts, will any of the survivors find a way to bring Cass down and make it off the island alive?

Ethan learns he carries the spirit of a warrior who battled dragons in 16th-century Korea -- and one day he'll find a tattooed girl carrying the spirit of that warrior's beloved. Years later, he meets Sarah and dragons soon descend on Los Angeles seeking out the two souls of the ancient lovers.

In the countryside, the boy Alan and his friend Becky steal a creepy wooden box with a powerful voodoo stick inside from his voodooistic neighbor. When the boy draws with the stick, his drunken father is attacked by a snake and vanishes. Years later, Alan and Becky are married to each other; while planting some flowers to celebrate the death of Alan's mother, Becky finds the box buried in the garden and she keeps the stick in her pocket. Meanwhile, five friends are traveling in a monster truck, drinking beer. The driver accidentally runs over Becky, but believes he had hit an animal. When Alan witnesses the hit-and-run and sees his wife dead, he uses the stick seeking revenge against the youngsters.

A dangerous horde of venomous snakes together with a giant boa escapes from a leather factory. Meanwhile, at a local girl's school, everyone is preparing for a graduation. However, it is suddenly stopped, after snakes attack schoolgirls. Will they escape and survive the monster's attack?

A group of American tourists heading down an African river make a brief stop at Snake Island, an island that has been virtually abandoned for years. When they end up getting trapped on the island overnight, they find thousands of deadly snakes intent on reclaiming the tropical island for themselves.

A team of environmentalists, including a reporter, her camera man, and an environmentalist's famous girlfriend charter a boat and with the captain, sail to a military island. They suspect the island is hosting to illegal activities. Upon arrival, however, they find no one. They finally reach a deserted house, where they find Dr. Susan Richardson, who tells them that everyone on the island is dead, including her father. Richardson's team were working on a compound that could make edible plants grow to super size, however the military intervened with plans of their own. They wanted to test the compound's effects on animals, and proceeded to feed it to several komodo dragons and cobras.

An oil company expedition disturbs the peace of a giant ape and brings him back to New York to exploit him.