When car dealer Charlie Babbitt learns that his estranged father has died, he returns home to Cincinnati, where he discovers that he has a savant older brother named Raymond and that his father's $3 million fortune is being left to the mental institution in which Raymond lives. Motivated by his father's money, Charlie checks Raymond out of the facility in order to return with him to Los Angeles. The brothers' cross-country trip ends up changing both their lives.

Photographer Robert Kincaid wanders into the life of housewife Francesca Johnson for four days in the 1960s.

A young couple is overjoyed when they find out that, after having had two girls, the wife is pregnant again, and this time it will be a son. However, the boy turns out to autistic. Unhappy with the diagnoses and treatments available, they decide to work out their own therapy program for their son.

A man with a low IQ has accomplished great things in his life and been present during significant historic events—in each case, far exceeding what anyone imagined he could do. But despite all he has achieved, his one true love eludes him.

A drama focused on the friendship between a high-functioning autistic woman and a man who is traumatized after a fatal car accident.

Jake, a high schooler on the autistic spectrum, feels disillusioned with the world. When he meets Alice, he begins to experience the world in other ways. Little does Jake know, Alice may have more in common with him than he could imagine.

Thomas is turning 16. His dad's in the army and they've just moved to a town in New South Wales; his mom is pregnant; his older brother, Charlie, who's autistic, has his own adolescent sexual issues. Thomas finds Charlie an embarrassment in public, so when Thomas is attracted to Jackie, a girl in his swim class, Charlie presents any number of obstacles when she drops by their house, when the three of them go for a walk, and during a family birthday dinner. Can Thomas find a way to enter the world of teen romance and still be his brother's keeper, or is Charlie's disability going to prove more than Thomas can handle?

An alcoholic becomes involved in a fellow A.A. member's plan to kidnap her young son from the boy's wealthy grandfather.

Harassed by bullies because of his mild autism, teen Ben finds refuge in an online computer game, which leads him to his virtual dream girl, Scarlite. Together, the odd couple seeks revenge against Ben's tormentors.

Renegade FBI agent Art Jeffries protects a nine-year-old autistic boy who has cracked the government's new "unbreakable" code.

Dr. John Carpenter takes the job of running a health center in a low-income district. He enlists three women to help out who — unbeknownst to him — are actually nuns in street clothes. The church wants to improve the neighborhood but fears that nuns in full habit would not be well received. Unaware of her unavailability, John falls for Sister Michelle, serenading her with his guitar — which, luckily for him, effectively wears away at her religious resolve.

A mentally challenged girl proves herself to be every bit as capable as her "perfect" sister when she moves into an apartment and begins going to college.