New York, I Love You delves into the intimate lives of New Yorkers as they grapple with, delight in and search for love. Journey from the Diamond District in the heart of Manhattan, through Chinatown and the Upper East Side, towards the Village, into Tribeca, and Brooklyn as lovers of all ages try to find romance in the Big Apple.

Eternal daydreamer Mel can't wait to quit her sucky catering job and fly to her dream destination: Portugal. Things change when the beautiful Jenny literally crashes into her life when Mel nearly runs her over in her classic BMW. It is love at first sight, however there is just one problem: Jenny mistakenly assumes Mel to be a boy. Despite this, the pair become boyfriend and girlfriend. With Mel attempting to disguise her true gender at every turn, her journey from tomboy to out lesbian is fraught with life-defining dilemmas and sweet surprises.

In late 1960s New York City, fed up with monotonous college life and police repression, free-spirited Fritz, an impenitent seducer and unrestrained party-animal, decides to explore the world. And just like that, as he flees NYC, heading to San Francisco, Fritz embarks on an endless adventure of illumination. Immersed in a world surrounded by drugs and sex, Fritz participates in mad orgies, brings about a revolution, incites mass urban riots, and crosses paths with drug-addled Nazi bikers.

An egotistical saxophone player and a young singer meet on V-J Day and embark upon a strained and rocky romance, even as their careers begin a long uphill climb.

A fateful night in 1959, four people die when the bus they are riding crashes. They continue as ghosts; their souls become eternally entwined to the life of a child born at the moment of their deaths as his guardians. Baby Thomas grows up to be a businessman who has memories of his playmates, but assumes they are products of his youthful imagination. When the ghosts realize they need Thomas' help to move on to the afterlife, they decide to make an appearance once more.

Henry Hackett is the workaholic editor of a New York City tabloid. He loves his job, but the long hours and low pay are leading to discontent. Also, publisher Bernie White faces financial straits, and has hatchet-man Alicia Clark—Henry's nemesis—impose unpopular cutbacks.

In the mid-1960s, wealthy debutant Edie Sedgwick meets artist Andy Warhol. She joins Warhol's famous Factory and becomes his muse. Although she seems to have it all, Edie cannot have the love she craves from Andy, and she has an affair with a charismatic musician, who pushes her to seek independence from the artist and the milieu.

New York, 1937. A teenager hired to star in Orson Welles' production of Julius Caesar becomes attracted to a career-driven production assistant.

A musician is offered a job in Vienna as stage director, but his disagreements with the aristocratic opera manager end in abrupt firing in spite of a mutual attraction. He's quickly engaged by another theatre and becomes famous for his lavish stage productions and fine acting, which begins their golden age with Suppé and Strauss.

While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.

Seen-it-all New York detective Frank Keller is unsettled - he has done twenty years on the force and could retire, and he hasn't come to terms with his wife leaving him for a colleague. Joining up with an officer from another part of town to investigate a series of murders linked by the lonely hearts columns he finds he is getting seriously and possibly dangerously involved with Helen, one of the main suspects.

Four unique high school show choirs in Ohio prepare themselves to win during their highly-anticipated, grueling and glamorous competition season.