In the early 1900s, the fictional Catfish Row section of Charleston, South Carolina serves as home to a black fishing community. Crippled beggar Porgy, who travels about in a goat-drawn cart, loves the drug-addicted Bess, who lives with stevedore Crown, the local bully.

Young William Shakespeare is forced to stage his latest comedy, 'Romeo and Ethel, the Pirate's Daughter', before it's even written. When lovely noblewoman Viola de Lesseps auditions for a role, they fall into forbidden love — and Shakespeare's play finds a new life (and title). As their relationship intensifies, the comedy soon transforms into tragedy.

In Martha's Vineyard, Mass., conjoined twins Walt and Bob Tenor make the best of their handicap by being the fastest grill cooks in town. While outgoing Walt hopes to one day become a famous actor, shy Bob prefers to stay out of the spotlight. When a fading Hollywood actress, Cher, decides to get her show "Honey and the Beaze" cancelled, she hires Walt -- and his brotherly appendage -- as her costars. But their addition surprisingly achieves the opposite.

Gabriel is a young, aspiring musical composer whose life seems stuck in the First Act. When his new musical number gets a critical reception, a theatre colleague, Perry, tells Gabriel that he needs to get a life before he can write about one – so he heads straight for his local gay bar.

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In the 1970s, Strange Fruit were it. They lived the rock lifestyle to the max, groupies, drugs, internal tension and an ex front man dead from an overdose. Even their demise was glamorous; when lightning struck the stage during an outdoor festival. Twenty years on, these former rock gods they have now sunk deep into obscurity when the idea of a reunion tour is lodged in the head of Tony, former keyboard player of the Fruits. Tony sets out to find his former bandmates with the help of former manager Karen to see if they can recapture the magic and give themselves a second chance.

In 1965, passionate musician Glenn Holland takes a day job as a high school music teacher, convinced it's just a small obstacle on the road to his true calling: writing a historic opus. As the decades roll by with the composition unwritten but generations of students inspired through his teaching, Holland must redefine his life's purpose.

Lucky Jackson arrives in town with his car literally in tow ready for the first Las Vegas Grand Prix - once he has the money to buy an engine. He gets the cash easily enough but mislays it when the pretty swimming pool manageress takes his mind off things. It seems he will lose both race and girl, problems made more difficult by rivalry from Elmo Mancini, fellow racer and womaniser.

Danny La Rue stars in this 1970s drag comedy as Fred Wimbush, a Shakespearean actor who is drafted into WWII and is appearing in a camp show in France when the Nazis advance. Unless he continues in his female costume, Fred is certain to be shot as a spy. The risque gags and double entendres fly as he attempts to make his escape in the company of a troupe of Girl Guides.

Juliet, a white girl, falls in love with a dark-skinned romeo, a divine trumpet player from the Roma orchestra. But her father Satchmo doesn't accept Romeo. Romeo needs to fight for Juliet at the legendary Festival of the trumpeters in Gucha.

Charlie Kaufman is a confused L.A. screenwriter overwhelmed by feelings of inadequacy, sexual frustration, self-loathing, and by the screenwriting ambitions of his freeloading twin brother Donald. While struggling to adapt "The Orchid Thief," by Susan Orlean, Kaufman's life spins from pathetic to bizarre. The lives of Kaufman and Orlean's book become strangely intertwined as each one's search for passion collides with the other's.

The aftermath of the events, and a new adventure... In the sequel, the heroes who are marrying by abducting their future wives, leave for their honeymoon in Georgia by train.