Five bizarre stories with no apparent connection to one another eventually become intertwined, resulting in surreal circumstances.

Josie, the daughter of the town's wealthiest businessman, faces problems at home and wishes to leave town but is disoriented. Her decision is finalized after she falls asleep in a Target dressing room. She awakens to find herself locked in the store overnight with the janitor, Jim, the town "no hoper" and liar.

Five grisly tales from a 1950s-style comic, including a murdered father rising from beyond, a bizarre meteor, a vengeful husband, a mysterious crate's occupant, and a plague of cockroaches.

Bounty hunters seek shelter from a raging blizzard and get caught up in a plot of betrayal and deception.

Aspiring director Corky St. Clair and the marginally talented amateur cast of his hokey small-town musical production go overboard when they learn that Broadway theater agent Mort Guffman will be in attendance.

During a trip to Denmark, a man is arrested and accused of murdering his wife and three children. Though maintaining his innocence, he remains jailed as police investigate.

Army psychiatrist Colonel Kane is posted to a secluded gothic castle housing a military asylum. With a reserved calm, he indulges the inmates' delusions, allowing them free rein to express their fantasies.

Bumbling bank janitor Ernest P. Worrell is assigned to jury duty, and soon finds himself in trouble when he is covertly switched with a look-a-like crime boss. Ernest must escape from jail to expose the mix-up.

Nate Johnson, a Los Angeles man estranged from his wife and three children, decides to reconnect with his family by taking them with him on a road trip to Missouri for a big family reunion.

Unpopular best friends PJ and Josie start a high school self-defense club to meet girls and lose their virginity. They soon find themselves in over their heads when the most popular students start beating each other up in the name of self-defense.

Josie, Melody and Val are three small-town girl musicians determined to take their rock band out of their garage and straight to the top, while remaining true to their look, style and sound. They get a record deal which brings fame and fortune but soon realize they are pawns of two people who want to control the youth of America. They must clear their names, even if it means losing fame and fortune.

The title is a portmanteau on kudomono (fruit) and nou (brains). The anime consists of three two-minutes skits, with basically the same structure. Orange and Pineapple are in Hong Kong, Ancient Egypt, Outer Space. Orange is trying to accomplish something - watching a drug deal go down, taking a break from work, trying to defuse a bomb outside a space station - while Pineapple pesters him with pointless and increasingly obscure questions.