Commissioner Tredwell is the law of the land and he gets whatever he wants with the help of hired guns and lackey lawyer Conners. The only one who publicly stands up to Tredwell is Beecham of the Clarion. Beecham has his paper burned to the ground and when he starts a petition to make Wyoming a state, taking the power away from Tredwell, he is killed. But when Kansas Kate comes in to visit her son Conners, she sees what is going on and she takes over the paper and keeps the pressure on Tredwill. With this Conners has mixed emotions, but the boys do everything they can to protect Kate and the paper. Written by Tony Fontana

The Three Mesquiteers, as army scouts, soothe hostilities between the Army and Indians after both have been riled by someone with a hidden agenda - a renegade chief, who is found to be masquerading as an Army interpreter.

The Mesquiteers try to help their friend build a telegraph system, despite a local newspaper editor's attempts to sabotage the lines.

Seraphim Cloud and his life size doppelgänger enter the netherworld of Calico Ghost Town deep within the Mojave Desert.

A crooked real estate manipulator sells worthless land on mortgage to flood refugees, then tries to profit by reselling the land to the state, committing murder in the process, as the Three Mesquiteers work to bring him and his gang to justice.

The Three Mesquiteers convince a group of settlers to exchange their present property for some which, unbeknownst to our goodguys, is going to be worthless. They are captured before they can warn the ranchers.

Stony Brooke, Rusty Joslin and Rico, known as The Three Mesquiteers, return to Oklahoma at the close of the Spanish-American War, and are concerned that some of their wounded buddies have no prospects for a satisfactory future. When the government offers preferred homesteads in the newly-opened Oklahoma territory to war veterans, they send word for their pals to join them there. Once there, the veterans meet a hostile reception as the cattlemen resent the influx of "nesters" and are determined to drive them out. Mace Liscomb and his brother Orv plan not only to drive out the homesteaders, but to also double cross the cattlemen and gain exclusive titles to the range lands for themselves. Stony and his pals eventually show the honest cattlemen that there is room for the settlers and that both are fighting a common enemy. Written by Les Adams

It's "The Three Mesquiteers" again. Gaucho escapes from Braden's gang only to be shot by them. The Mesquiteers drive away the outlaws and take his money on to his mother. But Isabella thinks Tucson is her long lost son and they don't have the heart to tell her he is dead.

The Cherokee Strip is off limits to the Rangers, so that is where badman Lemar operates from. When the Rangers capture his brother and the jury sentences him to hang, Lemar starts killing the jurists. Then the scoundrels kidnap the Captain's daughter Doris... Written by Tony Fontana

Johnny Mack Brown's Universal western series was drawing to a close when Cheyenne Roundup was released in mid-1943. Brown is herein cast in a dual role, as honest Gils Brandon and his less-than-honest brother Buck. Pursued by lawman Steve Rawlins (Tex Ritter), Buck tries to pass himself off as the upright Gils.

In 1867, a gang robs a bank and flees into the desert. Out of water, the outlaws encounter a ghost town called Yellow Sky and its only residents, a hostile young woman and her grandfather.

Dry Gulch Trading Post owner Kurt Fabian advances money on mortgages to the local settlers to finance an irrigation program. Rangers Tex Wyatt, Jim Steele and Panhandle Perkins transport the money in a strong box which they place in the Wells Fargo safe as Agent Sam Benson assures them that he is the only one who knows the safe combination.