Julius and Vincent Benedict are the results of an experiment that would allow for the perfect child. Julius was planned and grows to athletic proportions. Vincent is an accident and is somewhat smaller in stature. Vincent is placed in an orphanage while Julius is taken to a south seas island and raised by philosophers. Vincent becomes the ultimate low life and is about to be killed by loan sharks.

An anthology of eleven vignettes featuring star-studded casts of extremely unique individuals who all share the common activities of conversing while drinking coffee and smoking cigarettes.

Monty is a mechanic struggling to make ends meet as he raises his three young daughters. When the court awards custody of his daughters to his shady ex-wife, Monty desperately tries to win them back with the help of Julia, a beautiful, Ivy League-educated attorney. Monty and Julia couldn't be less alike, but a flame is ignited... touching off a firestorm of love and conflict.

Honors student Jane Ryan heads to Manhattan for a college-scholarship competition. Her rebellious twin Roxy tags along to crash a video shoot. But anything can happen – and does – in a romp involving a pursuing truant officer, a smuggler, hunkalicious guys, and the girls' realization that when the chips are down, a sister can be the best friend of all.

Leelee Sobieski is brash, abrasive and vulnerable as a teenage child of divorce who hides her pain behind a mask of hard-edged gothic rebellion. Albert Brooks plays a man who is her total opposite, a precise and well-ordered menswear store owner of forty-nine who manages limited expectations and protects lonely secrets with pleasant ritual and quiet, ironic reserve. These two total opposites collide in conflict then come together in a surprising alliance, changing each other's lives forever.

Lifelong friends Dave and Mitch are envious of the other's life. Mitch thinks Dave has it all: a beautiful, loving family and a high-paying job at a prestigious law firm. But Dave thinks Mitch’s stress-free playboy life without obligation or consequence is the real dream come true. One fateful drunken night, they both admit that they wish they had the other’s life while peeing in a fountain when lightning strikes. The next morning, they wake up, hungover, in each other’s bodies! With time not on their side, Mitch and Dave comically struggle to avoid completely destroying each other’s lives before they can find a way to get their old ones back.

Dallas, a successful executive with a beautiful wife, dreams of having a family, while his gay brother Austin dreams of winning a local drag show. By a twist of fate, the brothers switch bodies and have to see how the other lives.

David Grodin has an obsessive-compulsive personality. But he is also just plain obsessed with Maxine Smith, his ex-wife of five years and his business partner. Their small business is Mr & Mrs, a small swimwear company he founded but that only became successful when she became its creative director. They work well together and are best friends, but Max feels that they just could not live together and be married to each other. They learn that because of a legal technicality, their divorce was never executed and thus they are still legally married.

In the final minutes before oxygen depletion, deniers rant, couples combust, strangers collide - and one exhausted scientist races against time to save humanity.

After serving five years in prison, wild child Tanya looks to her buttoned-up, by-the-book sister Danica to help her get back on her feet. The feisty ex-con becomes suspicious and concerned when Danica tells her that she's in a long-distance, online relationship with a mysterious man she's never seen. As the polar opposites start to collide, Tanya soon discovers that her sibling's picture-perfect life may not be what it seems.

When Pollyanna is orphaned, she's sent to live with her crotchety Aunt Polly. Pollyanna discovers that many of the people in her aunt's New England hometown are as ill-tempered as her aunt. But Pollyanna's incurable optimism - exemplified by her "glad game", in which she looks for the bright side of every situation - brings a change to the staid old community.

Uptight and straight-laced, FBI Special Agent Sarah Ashburn is a methodical investigator with a reputation for excellence--and hyper-arrogance. Shannon Mullins, one of Boston P.D.'s "finest," is foul-mouthed and has a very short fuse, and uses her gut instinct and street smarts to catch the most elusive criminals. Neither has ever had a partner, or a friend for that matter. When these two wildly incompatible law officers join forces to bring down a ruthless drug lord, they become the last thing anyone expected: buddies.