Lawrence is an optimistic suit salesman for whom everything always goes right-until he takes the suicidal credit collector Holloman under his wing, and everything starts to go wrong. Very wrong.

Oregon, 1851. Hermann Kermit Warm, a chemist and aspiring gold prospector, keeps a profitable secret that the Commodore wants to know, so he sends the Sisters brothers, two notorious assassins, to capture him on his way to California.

Jean-Claude is a loud-mouthed, know-it-all and full time boor who is best friends with Stef, a self-styled lady killer who would do better with the fairer sex if he could work up the ambition to wake up in the morning. Stef has decided that he may need some help in finding the woman of his dreams, and embracing loyalty rather than logic he turns to Jean-Claude for advice.

Andy Stitzer has a pleasant life with a nice apartment and a job stamping invoices at an electronics store. But at age 40, there's one thing Andy hasn't done, and it's really bothering his sex-obsessed male co-workers: Andy is still a virgin. Determined to help Andy get laid, the guys make it their mission to de-virginize him. But it all seems hopeless until Andy meets small business owner Trish, a single mom.

Corporate billionaire Edward Cole and working class mechanic Carter Chambers are worlds apart. At a crossroads in their lives, they share a hospital room and discover they have two things in common: a desire to spend the time they have left doing everything they ever wanted to do and an unrealized need to come to terms with who they are. Together they embark on the road trip of a lifetime, becoming friends along the way and learning to live life to the fullest, with insight and humor.

Detectives Marcus Burnett and Mike Lowrey of the Miami Narcotics Task Force are tasked with stopping the flow of the drug Ecstasy into Miami. They track the drugs to the whacked-out Cuban drug lord Johnny Tapia, who is also involved in a bloody war with Russian and Haitian mobsters. If that isn't bad enough, there's tension between the two detectives when Marcus discovers that playboy Mike is secretly romancing Marcus’ sister, Syd.

Teenagers Solomon and Tummler kill time in Xenia, Ohio, a small town that has never recovered from the tornado that ravaged the community in the 1970s.

Harry hates being a TV producer and dreams of leaving his job to travel the world. He loves Alex, an aspiring actor who is struggling to create an identity for himself as a performer. Rugby player William's nine-year-old daughter is intent on sabotaging his relationships with new boyfriends, and he's finding it difficult to let Lawrence, the soap star, into his life. Lars is a handsome sometime-model kept by Tom, a successful artist, who will excuse his every betrayal so long as Lars doesn't leave him.

Youthful Father Chuck O'Malley led a colorful life of sports, song, and romance before joining the Roman Catholic clergy. After being appointed to a run-down New York parish, O'Malley's worldly knowledge helps him connect with a gang of boys looking for direction, eventually winning over the aging, conventional Parish priest.

A wealthy man, paralysed after an accident, hires a caregiver from a completely different background. The unlikely relationship between these two opposite characters soon transforms into an extraordinary and powerful friendship that changes both of their lives.

A happy-go-lucky Shobhan tries to help his friend improve his love life until things become complicated for both of them and tests their friendship.

When three childhood best friends pull a prank gone wrong, they invent the imaginary Ricky Stanicky to get them out of trouble. Twenty years later, the trio still uses the nonexistent Ricky as a handy alibi for their immature behavior. But when their spouses and partners get suspicious and demand to finally meet the fabled Mr. Stanicky, the guilty trio decide to hire a washed-up actor and raunchy celebrity impersonator to bring him to life.