Geoffrey Brooke, an African explorer, becomes a friend of Rodney Miller, a struggling young artist. Through his influence Miller becomes celebrated. Brooke is called to the Congo, leaving behind his bride of a few months. Miller is about to despair of finding a suitable model for his supreme artistic effort, a painting of Circe, the temptress, when Cleo, a bewitchingly beautiful woman enters and offers to pose for it.

Jimmy Nevins--once wealthy and now engaged to Doris Standish--is reduced to poverty and jilted by her when he is befriended by Mary Butler, the leader of a gang of crooks.

A man is shipwrecked on a South Seas island, and although he has a fiancee back home, he falls in love with a Polynesian girl. When his fiancee finally finds him and arrives on the island to take him home, she finds out that he refuses to leave the local girl, who is now the mother of his child.

The plot concerns a war hero who returns home determined to give up his old ways as a crook. Bud Doyle (Milton Sills) is still being hounded by the cops, and both his wife (Marcia Nanon) and a former associate, a dishonest politician, want to do him in.

Grace Ainsworth wants to return to her career as an opera singer, and her mother-in-law supports her. Grace's husband, Edwin, wants her to stay at home and to convince her, he relates the story of his latest play about a man who allows his wife to return to the stage. Edwin comes to believe that Grace is in love with Harold Chase, a manager, and the couple separates. Edwin has an affair with a dancer, Madeline, and he winds up in a fight with her dancing partner, Vincenti, which causes him to lose his memory.

Gordon Palmer is a lazy and cowardly rich man's son. When he and his fiancée, Aileen Merton, are held up by two crooks, Slug Williams and Beef O'Connell, he passively allows them to take whatever they want. At least he comes to life when they try to steal Aileen's engagement ring -- he scares them into giving that back. Aileen, however, is pretty fed up with him.

Jack Pickford got his own production company when his sister Mary signed a huge contract with First National, and this was its first product. the story takes place in the Blue Ridge mountains, where the Appersons and the Yartons have an ongoing feud.

The Isle of Lost Men is one of those lawless tropical island colonies so beloved of adventure-story writers.

Andrew Maxwell is so intent on creating a universal language that he completely neglects his wife, Laurette, and daughter, Ruth. Laurette decides she wants to return to the stage and is encouraged by Charles Prescott, a former suitor. When Maxwell discovers Laurette and Prescott together, he berates her, and she angrily moves out, taking Ruth along with her.

Felix, the King of Wallonia, has to marry Louise, Princess of the neighboring State of Trebizond. The old Prince, her father, craves the elixir of youth, and gets drunk so often that Trebizond is in bad shape. Thus, it is up to Felix to be King of both States. But Louise has a love affair with Stepan, the heir presumptive to his throne, and Felix flees to America in disguise. By a strange twist of circumstance he takes a job as butler in the home of J.P. Morton, multi-millionaire. There he meets Marcia, Morton's daughter, and the jig is up. He loves her.

Seduced and abandoned by the caddish Louis La Farge shepherdess Marie Beaupre is cast out of the village and forced to survive in the mountains alone. Driven mad she becomes known as “the witch woman” until hypnotist Dr. Cochefort and his friend Delaunay encounter her while on a hunting trip, take her to Paris, and effectuate a cure at which time she becomes heir to Delaunay's fortune. All seems clear sailing until Marie is introduced to Louis's twin brother Maurice and mistaking him for Louis sets forth on a plan for revenge.

Sato (Sessue Hayakawa) faithfully works for importer James Thornton (James Neill). When the old man dies, he leaves his daughter Mildred (Vivian Martin) in Sato's care. Sato loves the girl, but as he is Japanese he cannot hope to ever marry her (at least not in the racially prejudiced era of the early 1900s). Besides, Mildred loves Harry Maxwell (Tom Forman), who was raised alongside her.