Whatever Works explores the relationship between a crotchety misanthrope, Boris and a naïve, impressionable young runaway from the south, Melody. When Melody's uptight parents arrive in New York to rescue her, they are quickly drawn into wildly unexpected romantic entanglements. Everyone discovers that finding love is just a combination of lucky chance and appreciating the value of "whatever works."

Mel Edison has just lost his job after many years and now has to cope with being unemployed at middle age during an intense NYC heat wave.

Two championship rodeo partners travel to New York to find their missing friend, Nacho Salazar who went missing there.

A mischievous, adventuresome fourteen-year-old girl and her best friend begin following an eccentric concert pianist around New York City after she develops a crush on him.

Two cops are sent in to defuse a bomb, but when one of the cops has split personality disorder, it's up to the other to find the right personality before the ticking time bomb blows them up.

The life and work of New York artist Jean-Michel Basquiat have been marked by a long quest for identity, by his Haitian and Puerto Rican family origins and by a founding trip to Africa. To portray this major painter of the 20th century, who died in 1988 at only 27 years old, is also to evoke the place of black American artists in the conservative and racist America of the Reagan years.

Walid, a good-natured 25-year-old, tries to cheer up Sprite, his eco-anxious cousin, by inviting him to lunch at the brand new Kebab in Chelles. However, their day takes an unexpected turn when they find themselves facing a nervous robber.

Gladys Glover has just lost her modeling job when she meets filmmaker Pete Sheppard shooting a documentary in Central Park. For Pete it's love at first sight, but Gladys has her mind on other things, making a name for herself. Through a fluke of advertising she winds up with her name plastered over 10 billboards throughout city.

A desperate gallerist conspires to sell a dead body at Art Basel Miami.

Lucky is tricked into missing his own wedding to Margaret and has to make $25,000 so her father will allow him to marry her. He and business partner Pop go to New York where they run into dancing instructor Penny. She and Lucky form a successful dance partnership, but romance is blighted by his old attachment to Margaret and hers for Ricky.

Creeper helps friend and comedian Christina P rediscover her Inner Chola.

In the glamorous world of New York City, Rebecca Bloomwood is a fun-loving girl who is really good at shopping – a little too good, perhaps. She dreams of working for her favorite fashion magazine, but can't quite get her foot in the door – until ironically, she snags a job as an advice columnist for a financial magazine published by the same company.