Eva, a hermaphrodite from birth, with clear signs of both sexes, is raised under the strict guidance of her uncle, Professor Pissinger. The professor surgically implants a device called a "sexmaker" which allows Eva to control her sexual intensity. Unfortunately, this also puts her in the sights of an impotent gangster who wants the device for himself.

Paul, a 20 year old midwesterner, arrives at the central bus station and quickly catches eyes with Wye, a 22 year old girl voguing on the sidewalk. After Paul seeks her out in secret, an intense love between them blossoms. But when Paul discovers Wye is trans, he is forced to confront his own identity and what it means to belong.

Lia, a retired teacher from Georgia, learns from her young neighbor, Achi, that her long-lost transgender niece, Tekla, has crossed the border into Turkey. In search of Tekla, Lia travels to Istanbul with the unpredictable Achi, where they explore the hidden depths of the city.

In this documentary, a Hollywood hopeful immersed in geek subculture decides it's time to tell the world that he loves transgender women.

Ari can’t satisfy his wife Sara. He crashes his speedboat into a cliff and winds up in Switzerland for rehabilitation in what may or may not have been a suicide attempt. Alex, commissioned to paint Sara’s portrait by Ari, becomes Sara’s house guest and sex partner in Ari’s absence. Teresa, Ari’s secretary and ex-lover, is jealous of Sara’s relationship with Alex and schemes to break them up.

Wealthy Olga Arbant, with the help of her submissive husband Paul, enjoys kinky scenarios to help with the writing of her novels, as well as controlling everything and everyone. Impoverished Patrizia, who is a virgin, has agreed to do whatever Olga demands for one month. After being subjected to various humiliations, Patrizia frustrates Olga by developing a mind of her own.

A local Thai flight crashes inside Burma in rebel held territory. Amongst the survivors are several gay men and transsexuals. The Thai Army is ordered by the Foreign Ministry to rescue them. One of their soldiers is a bit of a loose cannon and he hates homosexuals as his son is one. However he must do his duty despite his prejudice.

A splendid doctor arrives in a small village: all the males compete to undergo repeated examinations in order to get to know the beautiful woman better. The mayor of the village, taking advantage of the beautiful "bait", would like to teach a lesson to the playboy Gustavo, who some time ago had caught all the husbands of the village.

A woman living in a small town discovers after fifty years that she is actually a man. Will she change her sex and suffer the reaction of a narrow-minded society?

Pasquale is a policeman in Roma. During a roundup he meets Desideria. He/she is a transsexual, living together with other two trans , Gaia and Gioia. But overall Desideria is an old friend of Pasquale, they already been attending the same schools. Desideria immediately fall in love for Pasquale. But the policeman has a fiancé, Nellina, even if too far so they meet rarely. That's why Pasquale could change idea about Desideria.

River goes to their first appointment at the “Gender Identity Disorder Unit”. There, River has to answer the psychiatrist's test that will decide if they will be able to access the care they need. River knows exactly what they has to say, but one small detail will endanger their plans.

A grieving husband struggles to come to terms with his wife's passing. Following a night-time visit to her grave, he picks up a transgender sex worker.