Whatever Works explores the relationship between a crotchety misanthrope, Boris and a naïve, impressionable young runaway from the south, Melody. When Melody's uptight parents arrive in New York to rescue her, they are quickly drawn into wildly unexpected romantic entanglements. Everyone discovers that finding love is just a combination of lucky chance and appreciating the value of "whatever works."

Mel Edison has just lost his job after many years and now has to cope with being unemployed at middle age during an intense NYC heat wave.

Two championship rodeo partners travel to New York to find their missing friend, Nacho Salazar who went missing there.

A mischievous, adventuresome fourteen-year-old girl and her best friend begin following an eccentric concert pianist around New York City after she develops a crush on him.

Gladys Glover has just lost her modeling job when she meets filmmaker Pete Sheppard shooting a documentary in Central Park. For Pete it's love at first sight, but Gladys has her mind on other things, making a name for herself. Through a fluke of advertising she winds up with her name plastered over 10 billboards throughout city.

Lucky is tricked into missing his own wedding to Margaret and has to make $25,000 so her father will allow him to marry her. He and business partner Pop go to New York where they run into dancing instructor Penny. She and Lucky form a successful dance partnership, but romance is blighted by his old attachment to Margaret and hers for Ricky.

In the glamorous world of New York City, Rebecca Bloomwood is a fun-loving girl who is really good at shopping – a little too good, perhaps. She dreams of working for her favorite fashion magazine, but can't quite get her foot in the door – until ironically, she snags a job as an advice columnist for a financial magazine published by the same company.

A clairvoyant woman thinks that she's met her future husband because she's seen him in a dream. They marry and he takes her back to his butcher shop in New York city, where her powers tend to influence everyone she meets while working in the shop. Through her advice, she helps others and eventually finds the true man of her dreams.

After her ex-boyfriend's acting career takes off, Samantha picks up the pieces to her broken heart and (so-called) acting career to rediscover her essence as a modern Latinx actress.

Rival reporters Sam Craig and Tess Harding fall in love and get married, only to find their relationship strained when Sam comes to resent Tess' hectic lifestyle.

Polar bear Norm and his three Arctic lemming buddies are forced out into the world once their icy home begins melting and breaking apart. Landing in New York, Norm begins life anew as a performing corporate mascot, only to discover that his new employers are directly responsible for the destruction of his polar home.

A trip to New York for a job interview turns into a trip to hell for a small town couple.