In post-9/11 New York City, an eclectic group of citizens find their lives entangled, personally, romantically, and sexually, at Shortbus, an underground Brooklyn salon infamous for its blend of art, music, politics, and carnality.

Anne, a newcomer to the workplace, was asked to deliver some documents to the CEO's house. However, she accidentally walked into the president's private SM game room. Before she could react, CEO Earl caught her in the act.

Erika Kohut, a sexually repressed piano teacher living with her domineering mother, meets a young man who starts romantically pursuing her.

Vittorio, an American novelist teaching in Rome, meets the beautiful but damaged Bianca and they rapidly fall into an urgent, tempestuous affair. He's hesitant over their relationship since she seems to thrive on conflict and is constantly baiting him into physical altercation. Bianca gives Vittorio an exquisite leather belt as a gift; he knows immediately that she wants him to whip her with it. Driven by his craving for her, Vittorio complies to Bianca's desire. Their relationship escalates into a dark realm of S&M which becomes more and more self-destructive.

In Kentucky, a transgender woman and her best male friend lament the lack of eligible partners and step across old boundaries of love and romance.

Guerrino, a prematurely widowed businessman, falls in love with Chantal, a former paratrooper in the German army who changed sex a few years earlier.

A young woman, recently released from a mental hospital, gets a job as a secretary to a demanding lawyer, where their employer-employee relationship turns into a sexual, sadomasochistic one.

The wealthy president of a company has built up an unpayable debt to a local crime lord, and to escape punishment he sells his famous dancer wife to the lecherous old man figuring a 90 year old can’t do too much bad with her. Perhaps not, but others can while he watches. She’s put on stage in an underground BDSM sex show and begins a spiraling decent from strongly independent woman to submissive sex slave

Laura and Massimo are back and hotter than ever. But the reunited couple's new beginning is complicated by Massimo’s family ties and a mysterious man who enters Laura’s life to win her heart and trust, at any cost.

Laura and Massimo's relationship hangs in the balance as they try to overcome trust issues while a tenacious Nacho works to push them apart.

After the death of his father, a 16-year-old boy struggles with anger and instability, distancing himself from his mother. His search for escape leads him to a lonely dominatrix living nearby, a woman accustomed to giving and controlling pain. Drawn to her world, he seeks both solace and love, while she finds herself pulled into a bond that neither expected but both need.

Hospital director Mamoru Watanabe and nurse Reiko had a secret affair, but their relationship comes to an end when a young nurse Yumiko appears. Jealous, Reiko conspires with her ex-husband to take Yumiko to an underground warehouse... A young and beautiful angel in white is beaten, and intense pain turns into pleasure...