Conducting clandestine experiments within the morgue at Miskatonic University, scientist Herbert West reveals to a fellow graduate student his groundbreaking work concerning the re-animation of fresh corpses.

Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.

A Seattle history professor, drawn back to his estranged family on the Oregon coast to execute his late mother's estate, is reacquainted with his best friend from childhood, with whom he has a long-awaited tryst. Caught in an accelerating series of events, he discovers aspects of his father's New Age cult which take on a dangerous and apocalyptic significance.

Unperturbed by the disastrous outcome of his previous meddling with the dead, Dr. West continues his research into the phenomenon of re-animation; only this time, he plans to create life – starting with the heart of his young protégé Dan's dearly deceased Meg Halsey.

The Resonator, a powerful machine that can control the sixth sense, has killed its creator and sent his associate into an insane asylum. When a psychiatrist becomes determined to continue the experiment, she unwittingly opens the door to a hostile parallel universe.

A dying professor leaves his great-nephew a collection of documents pertaining to the Cthulhu Cult. The nephew begins to learn why the study of the cult so fascinated his grandfather. Bit-by-bit he begins piecing together the dread implications of his grandfather's inquiries, and soon he takes on investigating the Cthulhu cult as a crusade of his own.

Charles Dexter Ward, a wealthy scientist, uses an ancient diary and human remains to begin a terrifying and bloody pursuit for immortality.

H.P. Lovecraft anthology is divided into four segments: "The Library" which is the wraparound segment involving Lovecraft's research into the Book of The Dead and his unwitting release of a monster and his writing of the following horror segments "The Drowned", "The Cold", and "Whispers".

When a virginal artist falls in love with a call girl, she turns out to be the chosen bride of the alien god Cthulhu. To save her, he must stop an ancient cult from summoning their god and destroying mankind.

After a drug deal gone wrong, a group of punks flee to a secluded mansion where the house itself begins to terrorize and kill the trespassers.

A man and his wife claim the mansion of his warlock ancestor burned alive in 1765.

A young man visits his fiancé's estate to discover that her wheelchair-bound scientist father has discovered a meteorite that emits mutating radiation rays that have turned the plants in his greenhouse to giants. When his own wife falls victim to this mysterious power, the old man takes it upon himself to destroy the glowing object with disastrous results.